Changes in version 1.1.5                        

  - Updated COAST to automatically add an intercept to the covar matrix
    if one is not detected. Likewise for CalcSumstats.

                        Changes in version 1.1.1                        

  - Updated COAST and COASTSS to return estimated effect sizes and
    standard errors from the allelic series burden test.

                        Changes in version 1.1.0                        

  - Added the ability to run COAST and COASTSS, as well as the component
    tests, with an arbitrary number of discrete annotation categories.
      - The updated code prefers integer annotation category labels
        starting at 1. However, the main functions will still
        support 0-indexed category labels.
  - Updated the data generating process DGP to simulate data with an
    arbitrary number of annotation categories.
  - Added vignettes on Data Generation and COAST-SS.
  - Updated CalcSumstats to bind all variant-level information
    (annotations, MAFs, betas, standard errors, p-values) into a single
    dataframe.

                        Changes in version 1.0.2                        

  - Streamlined and simplified the summary statistic-based allelic
    series baseline and sum tests, removing the need for meta-analysis
    or estimating cross category correlations.

                        Changes in version 1.0.0                        

  - Added ability to run COAST starting from summary statistics:
      - ASBTSS runs the allelic series burden test from summary
        statistics.
      - ASKATSS runs the allelic series SKAT test from summary
        statistics.
      - COASTSS runs the omnibus coding-variant allelic series test from
        summary statistics.
  - Added a CalcSumstats function to generate summary statistics from
    individual-level data.

                        Changes in version 0.6.0                        

  - Replaced the CountAlleles function with a similar (but faster)
    Counts function that returns counts the total number of alleles,
    variants, and carriers by variant class.
  - Updated the formatting of the results output by the main COAST
    function.

                        Changes in version 0.5.0                        

  - Added option (min_mac) to filter the variant set to only include
    those variants having at least a minimum minor allele count (10 is
    recommended).
  - Added a function (CountAlleles) to count the number of alleles of
    each variant category present in the genotype matrix. Also allows
    for counting the number of carriers of each type of allele.
  - By default, COAST now reports the number of alleles of each variant
    category that contributed to the test.